Zinc Oxide — The Gold-Standard Mineral UV Filter for Broad-Spectrum Sun Protection

Zinc Oxide (ZnO, CAS 1314-13-2) is an inorganic mineral compound and one of only two UV filters currently recognised as GRASE (Generally Recognized as Safe and Effective) by the US FDA — the other being Titanium Dioxide. It provides true broad-spectrum protection against both UVA and UVB radiation primarily by absorbing UV energy (with scattering as a secondary mechanism) while remaining on the skin surface. The SCCS has concluded that zinc oxide is safe as a UV filter at concentrations up to 25% for dermal application — and confirms that ZnO particles do not significantly penetrate intact human skin. SkinSenseDiary safety rating: 2/10 (low risk). No harmonised human health GHS classification under CLP Annex VI (environmental classifications may apply at supplier level). No allergen flags. No conflicts. Also used as a colorant (CI 77947). The SCCS has noted that ZnO nanoparticles in spray/aerosol products raise safety concerns due to inhalation risk. Found in 3,323 products.

Data sources: EU CosIng, SCCS opinions on zinc oxide (SCCS/1489/12, SCCS/O/137 — safe up to 25% for dermal use), US FDA (GRASE under OTC drug framework), ECHA CLP Annex VI (no harmonised human health classification), SkinSenseDiary internal safety evaluation, 3,323 products. Last updated: April 2026.

At a Glance

Also Known As
ZnO, CI 77947, 氧化鋅, 氧化锌, 酸化亜鉛 (JA), 징크옥사이드 (KO), Zinci Oxidum
CAS Number
1314-13-2
CosIng Functions
UV Filter, Colorant (CI 77947)
Source
Inorganic mineral compound; produced commercially by oxidation of zinc metal or zinc ore; naturally occurring as the mineral zincite
EU Regulation
Permitted UV filter (Annex VI); max 25%. Spray products raise inhalation safety concerns (SCCS).
Molecular Weight
81.38 Da (ZnO) — inorganic, does not significantly penetrate intact human skin

What Is Zinc Oxide?

Zinc Oxide (INCI: ZINC OXIDE, CAS 1314-13-2) is an inorganic mineral compound with the molecular formula ZnO and a molecular weight of 81.38 Da. It is a white, powdery solid that occurs naturally as the mineral zincite. In cosmetics, it serves two primary functions: as a UV filter providing broad-spectrum protection against both UVA and UVB radiation, and as a white colorant (CI 77947). Zinc oxide is one of only two UV filters currently classified as GRASE under the US FDA OTC drug framework — the other being Titanium Dioxide — reflecting its long history of safe and effective use in sun protection.


Unlike chemical (organic) UV filters such as avobenzone, homosalate, or octinoxate, zinc oxide is a physical (mineral/inorganic) UV filter. Modern research shows that zinc oxide works primarily by absorbing UV radiation (with scattering as a secondary mechanism) while remaining on the skin surface — the long-held belief that mineral sunscreens work mainly by "reflecting" UV is now considered outdated. The SCCS has confirmed through multiple opinions (SCCS/1489/12 and the 2014 revision SCCS/O/137) that zinc oxide particles — both nano and non-nano forms — do not significantly penetrate intact human skin. Small amounts of zinc ions may be released from the particles, but these quantities are negligible compared to baseline zinc levels already present in the body (zinc is an essential trace element). The SCCS concluded that zinc oxide is safe as a UV filter at concentrations up to 25% for products applied to the skin. Our database identifies zinc oxide in 3,323 products — the most of any UV filter.


A key safety distinction: while zinc oxide is safe for dermal application, the SCCS has noted that ZnO nanoparticles in spray or aerosol products raise safety concerns due to inhalation risk — inhaled ZnO nanoparticles can cause lung inflammation. This limitation applies specifically to nano-sized particles in aerosolised formats — it does not affect cream, lotion, stick, or non-spray liquid sunscreens. In the United States, the FDA's 2019 proposed sunscreen monograph update reaffirmed zinc oxide's GRASE status, while requesting additional safety data for several chemical UV filters. Zinc oxide has no harmonised human health GHS classification under CLP Annex VI (environmental classifications such as H410 may appear in supplier self-classifications), no allergen flags, and no conflicts in our ingredient database. No CIR Expert Panel safety assessment exists specifically for zinc oxide, as it is primarily regulated as an OTC drug ingredient in the US rather than a cosmetic ingredient.

What Does Zinc Oxide Do for Your Skin?

☀️

Broad-Spectrum UV Protection (UVA + UVB)

Zinc oxide is one of very few single ingredients that provides true broad-spectrum protection across the entire UV spectrum — from UVA I (340–400 nm), UVA II (320–340 nm), to UVB (290–320 nm). Most chemical UV filters cover only a portion of this range and must be combined with other filters to achieve broad-spectrum coverage. Zinc oxide's broad coverage makes it particularly effective at protecting against UVA-induced photoageing, hyperpigmentation, and long-term skin damage, in addition to UVB-induced sunburn.

🛡️

Mineral Surface Filter — Minimal Skin Penetration

As a mineral filter, zinc oxide works primarily by absorbing UV radiation (with scattering as a secondary mechanism) while remaining on the skin surface. The SCCS confirms that ZnO particles do not significantly penetrate intact human skin — meaning no meaningful systemic absorption occurs, though trace amounts of zinc ions may be released (negligible compared to baseline body zinc levels). This is a significant advantage for those concerned about chemical filter absorption (the FDA has documented systemic absorption of several chemical UV filters above proposed safety thresholds). Zinc oxide begins working immediately on application — there is no 15–20 minute wait time as recommended for some chemical sunscreens.

🩸

Sensitive Skin Compatibility

Zinc oxide's non-penetrating mechanism makes it the UV filter of choice for sensitive, reactive, and compromised skin. It is routinely recommended for babies, individuals with rosacea, eczema, or post-procedure skin, and during pregnancy. Zinc oxide is less likely to cause stinging, irritation, or allergic contact dermatitis compared to chemical UV filters. Its anti-inflammatory properties (zinc is a known anti-inflammatory agent) can actually help calm reactive skin. Many paediatric and dermatologist-recommended sunscreens use zinc oxide as their primary or sole UV filter.

💡

Mild Antimicrobial & Soothing Properties

Beyond UV protection, zinc oxide has mild antimicrobial and anti-inflammatory properties. Zinc compounds have been used medicinally for centuries — zinc oxide paste (e.g., calamine lotion) is a well-established treatment for skin irritation, nappy rash, and minor wounds. In sunscreen formulations, these ancillary properties can benefit acne-prone skin (mild antibacterial action) and sensitive skin (anti-inflammatory soothing). Zinc oxide is generally considered non-comedogenic and is often included in formulations designed for oily and acne-prone skin types.

Suitable for: All skin types, including sensitive, reactive, rosacea-prone, eczema-prone, acne-prone, and post-procedure skin. Routinely recommended during pregnancy and nursing. Suitable for babies and children. Particularly recommended for those who experience irritation from chemical UV filters, or who prefer a non-penetrating sunscreen option. Available in both nano (more cosmetically elegant, less white cast) and non-nano formats.

Is Zinc Oxide Safe?

2 / 10

Low Risk — FDA GRASE, SCCS Safe up to 25%

Zinc Oxide carries a SkinSenseDiary safety rating of 2/10 — low risk. It is one of only two UV filters with GRASE recognition under the US FDA OTC drug framework. The SCCS has concluded it is safe at up to 25% for dermal application, and confirms that ZnO particles do not significantly penetrate intact human skin. No harmonised human health GHS classification under CLP Annex VI, no allergen flags, and zero conflicts. The primary limitation is that spray/aerosol products containing ZnO nanoparticles raise safety concerns according to the SCCS due to inhalation risk — choose cream, lotion, or stick formats instead. Found in 3,323 products in our database.

Our rating is based on
US FDA
GRASE — Safe & Effective
The US FDA classifies zinc oxide as GRASE (Generally Recognized as Safe and Effective) under its OTC drug framework as a sunscreen active ingredient — one of only two UV filters with this status (alongside Titanium Dioxide). The FDA's 2019 proposed sunscreen monograph update reaffirmed this classification, while requesting additional safety data for 12 chemical UV filters. Zinc oxide is approved at concentrations up to 25% in the US. Its GRASE status reflects decades of safe use and an extensive body of safety data.
SCCS (EU Scientific Committee)
Safe up to 25% (Dermal)
The SCCS has evaluated zinc oxide in multiple opinions (SCCS/1489/12, SCCS/O/137) and concluded it is safe as a UV filter for cosmetic products applied to the skin at concentrations up to 25%. Both nano and non-nano forms are considered safe for dermal use. ZnO particles do not significantly penetrate intact human skin. However, the SCCS has specifically stated that nano ZnO in spray products raises safety concerns due to inhalation risk, which may cause lung inflammation.
GHS Hazard Classification (ECHA)
No Harmonised Human Health Classification
Zinc oxide has no harmonised human health GHS classification under CLP Annex VI — meaning no human health H-codes are assigned in the EU's official harmonised classification system. This covers: no oral toxicity (no H302), no skin irritation (no H315), no eye damage (no H318/H319), no respiratory irritation (no H335), no skin sensitisation (no H317), and no reproductive toxicity (no H361d). Note: environmental classifications such as H410 (very toxic to aquatic life) may apply at supplier level through self-classification (SDS) — harmonised classification and supplier self-classification can differ.
Allergens & Skin Sensitisation
Low Sensitisation Risk
No allergen flags in our database. No H317 (skin sensitisation) in the harmonised GHS classification. Zinc oxide is an inorganic mineral compound that remains primarily on the skin's surface, with minimal penetration into deeper layers. It is one of the most well-tolerated UV filters available, routinely used on babies, post-procedure skin, and individuals with eczema and rosacea. Allergic contact dermatitis to zinc oxide is extremely rare in clinical literature. Any irritation from a zinc oxide product is far more likely due to other ingredients in the formulation than to ZnO itself.

Things to Know

Inhalation safety concern in spray/aerosol products (SCCS): The SCCS has specifically stated that zinc oxide nanoparticles in spray products raise safety concerns due to inhalation risk. Inhaled ZnO nanoparticles can cause inflammation in the lungs. This applies to aerosol sprays and potentially to powder formats. If you use zinc oxide sunscreen, choose cream, lotion, fluid, or stick formats. Non-nano zinc oxide in non-spray products does not carry this concern. This limitation is about the delivery format, not the ingredient itself.

White cast: Zinc oxide is a white mineral that can leave a visible white residue on the skin — particularly noticeable on darker skin tones. Non-nano (larger particle) zinc oxide produces a stronger white cast than nano zinc oxide. Tinted zinc oxide sunscreens can address this issue. Formulation technology has improved significantly, and many modern zinc oxide sunscreens minimize white cast through particle size optimisation, tinting, and formulation engineering. If white cast is a concern, look for tinted formulations or nano zinc oxide in non-spray formats.

Nano vs non-nano — both safe on skin: The SCCS has confirmed that both nano and non-nano zinc oxide are safe for application to the skin at up to 25%. Neither form significantly penetrates intact human skin. The "nano" distinction matters primarily for inhalation exposure (sprays) and cosmetic elegance (white cast). Non-nano provides effective protection with a thicker, more visible finish; nano provides a more transparent, cosmetically elegant finish. Both are equally effective at UV protection when properly formulated.

Reapplication is essential: Like all sunscreens, zinc oxide products must be reapplied every 2 hours during prolonged sun exposure, and immediately after swimming, sweating, or towel-drying. No sunscreen — mineral or chemical — provides all-day protection from a single application. Zinc oxide has an advantage in that it provides immediate protection upon application (no wait time required).

Pregnancy & Nursing

Zinc oxide is widely regarded as among the most well-tolerated UV filters during pregnancy and nursing. As a mineral UV filter, it remains primarily on the skin surface — the SCCS confirms that ZnO particles do not significantly penetrate intact human skin, meaning systemic exposure is negligible. Zinc oxide has no harmonised GHS reproductive or developmental toxicity codes under CLP Annex VI (no H361d, no H362). Zinc oxide sunscreens are routinely recommended by dermatologists and obstetricians as a preferred sun protection option during pregnancy, particularly as an alternative to chemical UV filters — some of which (e.g., oxybenzone, octinoxate) have raised concerns about endocrine activity and have been detected in breast milk and blood. Both nano and non-nano forms are considered safe for dermal application during pregnancy. Sun protection itself is particularly important during pregnancy, as hormonal changes increase susceptibility to melasma (pregnancy mask). Consult your healthcare provider for individualised advice.

Safety data compiled from SCCS opinions on zinc oxide (SCCS/1489/12, SCCS/O/137 — safe up to 25% for dermal use; spray products raise inhalation concerns), US FDA GRASE classification (OTC drug framework), ECHA CLP Annex VI (no harmonised human health classification), published clinical and toxicological literature, SkinSenseDiary database analysis (3,323 products). No CIR Expert Panel assessment for zinc oxide. This is for educational purposes only and does not constitute medical or dermatological advice. Always consult a healthcare provider before changing your skincare routine, especially during pregnancy. Last updated: April 2026.

How to Use Zinc Oxide Sunscreen

1

Apply as the Last Step of Morning Skincare

After cleansing, toning, applying serums, and moisturising, apply zinc oxide sunscreen as the final step of your morning skincare routine. Sunscreen should always be the last skincare product applied (before makeup). Zinc oxide provides immediate protection upon application — unlike some chemical sunscreens, there is no 15–20 minute wait time.

2

Use the Right Amount — The Two-Finger Rule

Most people apply far too little sunscreen. For the face alone, use approximately two finger-lengths of product (about 1/4 teaspoon or 1.25 ml). Apply evenly to the face, ears, and neck. Do not forget the backs of hands if they will be exposed. For the entire body, approximately 35 ml (about 7 teaspoons) is needed for full coverage. Insufficient application dramatically reduces the effective SPF.

3

Reapply Every 2 Hours

No sunscreen provides all-day protection from a single application. Reapply every 2 hours during prolonged sun exposure, and immediately after swimming, heavy sweating, or towel-drying — even if using a water-resistant formula. For office workers with minimal sun exposure, a morning application with a midday touch-up is generally sufficient. Powder and stick zinc oxide products can be convenient for reapplication over makeup.

4

Choose the Right Format for Your Needs

Zinc oxide sunscreens come in various formats — cream, lotion, fluid, tinted, stick, and hybrid (zinc oxide + chemical filters). Choose based on your skin type, lifestyle, and cosmetic preferences. If white cast is a concern, try tinted or nano formulations. If you have acne-prone skin, look for oil-free fluid formats. Avoid aerosol/spray zinc oxide products containing nanoparticles (the SCCS has noted inhalation safety concerns for this format).

Which Product Format?

☀️

Mineral Sunscreen (Pure ZnO)

100% mineral formulation using zinc oxide (often combined with titanium dioxide) as the only UV filters. Best for sensitive skin, babies, and during pregnancy. May have more visible white cast. SPF 30–50+ available.

🎨

Tinted Mineral Sunscreen

Zinc oxide sunscreen with added iron oxide tints that eliminate white cast and provide light coverage. Iron oxides also offer additional protection against visible light and blue light. Excellent for daily wear under or instead of makeup.

💧

Hybrid (Mineral + Chemical)

Combines zinc oxide with chemical UV filters for better cosmetic elegance while maintaining broad-spectrum coverage. Lighter texture, less white cast. Good balance of protection and wearability. Not suitable if you want to avoid chemical filters entirely.

Pairing Guide for Zinc Oxide Sunscreen

✓ Compatible Pairings

Niacinamide (Vitamin B3)

An excellent pairing. Niacinamide strengthens the skin barrier, regulates sebum, and has brightening and anti-inflammatory effects — all of which complement zinc oxide sunscreen. Neither ingredient interacts negatively with the other. Apply niacinamide serum first, then zinc oxide sunscreen on top.

Hyaluronic Acid & Ceramides

Hydrating ingredients layer well under zinc oxide sunscreen. Apply hyaluronic acid serum and/or ceramide moisturiser first, allow to absorb, then apply zinc oxide sunscreen as the final step. The hydrating layers help zinc oxide spread more evenly and can reduce the drying feel some mineral sunscreens have.

Retinol (Evening Only)

Retinol increases UV sensitivity, making daily sunscreen essential. Zinc oxide is an ideal sunscreen partner for retinol users — it provides immediate, broad-spectrum protection with minimal skin penetration. Use retinol in the evening, zinc oxide sunscreen in the morning. This combination is one of the most recommended dermatological routines for anti-ageing.

⚠ Use with Care

Low-pH Vitamin C (L-Ascorbic Acid)

L-ascorbic acid serums with a pH below 3.5 may theoretically affect zinc oxide stability, though in practice most well-formulated products coexist without issues. Apply vitamin C serum first, wait 10–15 minutes for it to absorb and the pH to neutralise, then apply zinc oxide sunscreen. Some dermatologists recommend using vitamin C in the evening if you find the combination pills or feels unstable.

AHAs / BHAs (Morning Use)

If using glycolic acid, lactic acid, or salicylic acid in the morning, zinc oxide sunscreen is a good protective partner — these exfoliants increase UV sensitivity, and zinc oxide provides reliable broad-spectrum protection. However, some acid products can destabilise mineral sunscreen formulations. Apply acid, wait for absorption, then apply sunscreen. If pilling occurs, adjust your layering order or consider using acids in the evening only.

Heavy Silicone-Based Products

Layering multiple silicone-heavy products (primers, foundations) over zinc oxide sunscreen can cause pilling, balling, or an uneven finish. Zinc oxide sunscreens themselves often contain dimethicone. To reduce pilling: allow each layer to fully dry before applying the next, use lighter formulations, or choose a tinted zinc oxide sunscreen that replaces your foundation step.

Popular Products with Zinc Oxide

ANESSA
Mineral UV Sunscreen Mild Gel
Sunscreen
Beauty of Joseon
Daily Tinted Fluid Sunscreen SPF30
Sunscreen
Canmake
Mermaid Skin Gel UV
Sunscreen
100% Pure
Fruit Pigmented Tinted Moisturizer
Sunscreen
100% Pure
Green Tea SPF 30
Sunscreen
001 Skincare
Zinc & Protein A+ Clarifying Comfort Cream
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Showing 6 of 3,323 products containing Zinc Oxide. Product inclusion does not imply endorsement.

Frequently Asked Questions

Is Zinc Oxide safe for sensitive skin?
Zinc Oxide has a SkinSenseDiary safety rating of 2/10 (low risk) and is one of only two UV filters currently recognised as GRASE under the US FDA OTC drug framework. It has no harmonised human health GHS classification under CLP Annex VI, no allergen flags, and no conflicts in our database. The SCCS has concluded that zinc oxide is safe as a UV filter at concentrations up to 25% for dermal application. As a mineral UV filter, it works primarily by absorbing and scattering UV radiation within the upper layers of the skin (with absorption being the dominant mechanism) — the SCCS confirms that ZnO particles do not significantly penetrate intact human skin. This makes it particularly well-suited for sensitive skin, including babies and those with conditions like rosacea or eczema. Found in 3,323 products.
Can I use Zinc Oxide sunscreen every day?
Yes — daily use is not just safe, it is recommended. Zinc oxide sunscreen is designed for everyday use as part of a morning skincare routine. Because it is a mineral filter that does not significantly penetrate the skin, there are no cumulative exposure concerns. Apply as the last step of your morning skincare routine (after moisturiser, before makeup) and reapply every 2 hours during prolonged sun exposure. Zinc oxide provides immediate protection upon application — unlike some chemical filters that require a 15–20 minute wait. The SCCS has confirmed zinc oxide is safe at concentrations up to 25% for daily dermal application.
Is Zinc Oxide safe during pregnancy?
Zinc oxide is widely regarded as among the most well-tolerated UV filters during pregnancy and nursing. As a mineral UV filter, it remains primarily on the skin surface — the SCCS confirms that ZnO particles do not significantly penetrate intact human skin, meaning systemic exposure is negligible. It has no harmonised GHS reproductive or developmental toxicity codes. Zinc oxide sunscreens are routinely recommended by dermatologists and obstetricians during pregnancy, particularly as an alternative to chemical UV filters (some of which have raised endocrine disruption concerns). Both nano and non-nano forms are considered safe for dermal application during pregnancy. Consult your healthcare provider for individualised advice.
What is the difference between nano and non-nano Zinc Oxide?
The distinction refers to particle size. Non-nano zinc oxide has particles larger than 100 nanometres — effective UV protection but more visible white cast. Nano zinc oxide has particles smaller than 100 nm — more cosmetically elegant (less white cast) but with inhalation safety concerns. The SCCS has concluded that both forms are safe for dermal application at up to 25%, as neither significantly penetrates intact human skin. However, the SCCS has specifically stated that nano ZnO in spray products raises safety concerns due to inhalation risk. If you prefer nano zinc oxide for its cosmetic elegance, choose cream, lotion, or stick formats rather than aerosol sprays.
How does Zinc Oxide compare to chemical sunscreen filters?
Zinc oxide is a mineral UV filter that works primarily by absorbing and scattering UV radiation (with absorption being the dominant mechanism). Chemical filters also absorb UV and convert it to heat — they function primarily within the upper layers of the skin (stratum corneum), not through deep systemic absorption. Zinc oxide advantages: broad-spectrum UVA+UVB from a single ingredient, minimal skin penetration, immediate protection, GRASE status under the US FDA OTC drug framework. Trade-offs: white cast (especially non-nano), thicker texture, potential for pilling under makeup. Some chemical filters have faced scrutiny over potential endocrine activity, whereas zinc oxide has no such concerns given its negligible systemic absorption. Many dermatologists consider mineral sunscreens among the most well-tolerated options overall.
Does Zinc Oxide clog pores or cause breakouts?
Zinc oxide itself is generally considered non-comedogenic and is often included in formulations for acne-prone skin. Zinc compounds have mild antibacterial and anti-inflammatory properties that can benefit acne-prone skin. However, whether a specific product causes breakouts depends on the overall formulation — other ingredients (emollifiers, silicones, fragrances) may contribute. Look for zinc oxide sunscreens labelled "non-comedogenic" or "oil-free," and consider lighter formats like fluids rather than thick creams. Zinc oxide sunscreens tend to be better tolerated by acne-prone skin than many chemical sunscreen formulations.

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