Salicylic Acid — The Gold-Standard BHA for Acne & Pore Control

Salicylic Acid is a beta hydroxy acid (BHA) — a lipophilic (oil-soluble) exfoliant that penetrates into pores to dissolve sebum and dead cells, making it the gold standard for acne-prone and oily skin. Derived from willow bark or commercially synthesized, it has a molecular weight of 138.12 Da and is registered as EU CosIng #37595. CIR classifies it as "Safe with Qualifications." The SCCS (June 2023) confirms safety at ≤2% leave-on products and ≤3% rinse-off, with specific limits for sensitive areas. Often better tolerated than glycolic acid for oily and acne-prone skin, it does NOT increase UV sensitivity. Found in 7,115 products.

Data sources: EU CosIng (#37595), CIR Expert Panel (Safe with Qualifications), SCCS/1646/22 (June 2023), SCCS/1675/25 (April 2025 — children concerns), ECHA Annex VI GHS classification, SkinSenseDiary internal safety evaluation, 7,115 products. Last updated: April 2026.

At a Glance

Also Known As
BHA, Beta Hydroxy Acid, 水楊酸, 水杨酸, Ácido Salicílico
CAS Number
69-72-7
CosIng Functions
Exfoliant, Skin Conditioning, Preservative, Fragrance/Denaturant
Source
Naturally derived from willow bark; mostly produced via chemical synthesis
EU Regulation
Annex III/98 + Annex V/3 with concentration limits (≤2% leave-on, ≤3% rinse-off, ≤0.5% body lotion)
Molecular Weight
138.12 Da (C₇H₆O₃) — oil-soluble, pore-penetrating

What Is Salicylic Acid?

Salicylic Acid (INCI: SALICYLIC ACID, CAS 69-72-7) is a beta hydroxy acid (BHA) — a lipophilic (oil-soluble) organic acid with a phenolic structure. Unlike alpha hydroxy acids (AHAs) which are water-soluble, salicylic acid's oil-soluble nature allows it to penetrate into sebum-filled pores and dissolve the waxy substances that clog them. It has a molecular weight of 138.12 Daltons and is registered in the EU CosIng database (#37595) with functions as an exfoliant, skin conditioning agent, preservative, and fragrance/denaturant agent.


Salicylic acid is one of the most widely used active ingredients in acne and pore-care products worldwide. It works by breaking apart the intercellular lipids that bind dead skin cells and sebum (keratolytic and comedolytic effects), reducing bacterial colonisation (mild bacteriostatic effect, secondary to its primary keratolytic action), and reducing inflammation (anti-inflammatory effects). It is used in treatments for acne, blackheads, enlarged pores, dandruff, and warts. The CIR Expert Panel classifies it as "Safe with Qualifications" — meaning it is safe when formulated at appropriate concentrations, with suitable pH, and accompanied by appropriate use instructions. Our database identifies salicylic acid in 7,115 products, making it one of the most popular active exfoliants available.


The SCCS (Scientific Committee on Consumer Safety) evaluated salicylic acid extensively (SCCS/1646/22, June 2023) and confirmed safety at regulated concentrations: ≤2% for leave-on face products (and most body uses); ≤3% for rinse-off hair and body products; ≤0.5% for body lotion, eye care, lip care, deodorant, and oral care products; and ≤0.5% as a preservative. Salicylic acid carries multiple GHS hazard codes for the raw material (H302, H312, H315, H317, H318, H319, H361, H361d, H370, H372) — these apply to the concentrated chemical, not cosmetic formulations. A key advantage over AHAs: salicylic acid has NO photo-irritant or photosensitising properties (SCCS confirmed), so it does not increase UV sensitivity. However, SCCS/1675/25 (April 2025) raised safety concerns for children 3–10 years at aggregate exposure levels, and salicylic acid is not permitted for children under 3.

What Does Salicylic Acid Do for Your Skin?

Acne & Breakout Control

Salicylic acid is oil-soluble, allowing it to penetrate into sebum-clogged pores far more effectively than water-soluble AHAs. It dissolves the waxy sebum and dead cells that form comedones, prevents new breakouts, and reduces existing acne without over-drying the skin. Ideal for oily, acne-prone, and combination skin types.

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Pore Refinement & Texture

By unclogging pores and removing dead cell buildup, salicylic acid visibly reduces the appearance of enlarged, congested pores. Skin texture smooths as pore blockages clear and sebum production normalises. Results are often noticeable within 2–4 weeks of consistent use.

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Anti-Inflammatory & Redness Reduction

Salicylic acid has aspirin-related anti-inflammatory properties that calm active inflammation, reduce post-inflammatory hyperpigmentation, and soothe redness associated with acne. This often makes it better tolerated than glycolic acid for oily, acne-prone, and inflamed skin — though at higher concentrations it can be equally irritating, and sensitive skin should still patch-test first.

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Gentle Exfoliation Without UV Sensitivity

Unlike glycolic acid (AHA), salicylic acid is NOT a photosensitiser and does NOT increase UV sensitivity (SCCS confirmed). This means you can use it morning or evening without heightened sunburn risk. Often better tolerated than glycolic acid for oily and combination skin types, though at higher concentrations it can be equally irritating.

Suitable for: Oily, acne-prone, combination, and congested skin. Use with caution on dry, sensitive, or eczema-prone skin. Not recommended for very young children (under 3: prohibited; 3–10: safety concerns at aggregate exposure per SCCS/1675/25). Always start at low concentration and build tolerance gradually.

Is Salicylic Acid Safe?

3 / 10

Low Risk — Well-Studied with Clear Regulatory Limits

Salicylic Acid carries a SkinSenseDiary safety rating of 3/10 — low risk. The CIR Expert Panel concluded it is "Safe with Qualifications" — safe when used at regulated concentrations (≤2% leave-on, ≤3% rinse-off) with appropriate formulation. The SCCS confirmed these concentration limits are safe with a margin of safety (MoS) of 167 at the precautionary scenario — well above the threshold of 100 for adequacy. Raw salicylic acid carries multiple GHS hazard codes including H361d (developmental toxicant), but dermal absorption reaches up to ~60% under maximum experimental conditions (real-world cosmetic exposure is considerably lower) and systemic exposure at cosmetic concentrations is minimal. Low sensitisation risk at cosmetic levels (SCCS: Buehler and LLNA tests negative, though rare individual reactions may occur). Often better tolerated than glycolic acid for oily and acne-prone skin.

Our rating is based on
CIR Expert Panel
Safe with Qualifications
The Cosmetic Ingredient Review Expert Panel assessed salicylic acid and concluded it is safe when formulated at appropriate concentrations (≤2% leave-on, ≤3% rinse-off), with suitable pH and formulation to avoid irritation, and when product labelling includes appropriate use directions and warnings. This is a qualified safety determination contingent on proper concentration and use.
SCCS/1646/22 (EU, June 2023)
Safe at Regulated Limits — MoS 167
The SCCS confirmed salicylic acid is safe at ≤2% leave-on (face), ≤3% rinse-off, ≤0.5% body lotion/eye/lip/deodorant. Margin of safety (MoS) of 167 at the probabilistic scenario — well above 100 (adequate). NOAEL (no observed adverse effect level) 75 mg/kg bw/day in animal studies. Dermal absorption up to ~60% under experimental conditions (real-world exposure considerably lower); systemic exposure at cosmetic levels minimal. Not for spray/aerosol products (inhalation risk). Prohibited for children under 3; safety concerns for 3–10 year-olds at aggregate exposure (SCCS/1675/25, April 2025).
GHS Hazard Classification (ECHA)
10 Hazard Codes — Significant Raw Material Risks
Pure salicylic acid carries: H302 (harmful if swallowed), H312 (harmful in contact with skin), H315 (causes skin irritation), H317 (may cause allergic skin reaction), H318 (causes serious eye damage), H319 (causes serious eye irritation), H361 (suspected reproductive harm), H361d (suspected of damaging the unborn child — Repr. 2), H370 (causes organ damage), H372 (causes organ damage through prolonged exposure). These apply to the raw material — cosmetic formulations at 0.5–3% with buffered pH have a substantially lower hazard profile.
Allergens & Skin Sensitisation
No Skin Sensitisation at Cosmetic Concentrations
No allergen flags in our database. SCCS found low sensitisation risk via Buehler test and LLNA (local lymph node assay) — both negative at cosmetic concentrations. The H317 code (may cause allergic skin reaction) applies to the raw material. Skin irritation (stinging, redness) at higher concentrations is irritant-mediated, not allergic. True allergic contact dermatitis to salicylic acid is extremely rare.
GHS Hazard Flags (ECHA Annex VI — Raw Material)
Skin & Eye
H312 / H315 / H318 / H319
Harmful in contact with skin (H312), causes skin irritation (H315), causes serious eye damage (H318), causes serious eye irritation (H319) at full concentration. At cosmetic concentrations (0.5–3%) with buffered pH, irritation is the primary concern. Eye contact should be strictly avoided with all salicylic acid products.
Reproductive / Developmental
H361 / H361d — Repr. 2 (Developmental Toxicant)
H361: Suspected of damaging fertility or the unborn child. H361d: Suspected of damaging the unborn child — Repr. 2. SCCS NOAEL 75 mg/kg bw/day. Salicylic acid crosses the placenta. At cosmetic concentrations with dermal absorption of up to ~60% under experimental conditions (real-world exposure lower), systemic exposure is minimal. However, oral salicylates (e.g., aspirin) are known developmental toxicants. Topical salicylic acid at cosmetic concentrations is generally considered low risk, but caution during pregnancy is advised — see pregnancy section below.
Systemic
H370 / H372
H370: Causes organ damage. H372: Causes organ damage through prolonged exposure. For the raw material at high concentrations. The SCCS found that 10% salicylic acid lotion did not significantly increase systemic absorption. At cosmetic concentrations, organ exposure is expected to be below concern levels.
Inhalation & Ingestion
H302
Harmful if swallowed (H302). Not relevant to normal topical cosmetic use. Relevant for occupational handling and spray/aerosol product formulations (which are NOT recommended for salicylic acid due to inhalation risk).

Things to Know

Does NOT increase UV sensitivity: Unlike glycolic acid and other AHAs, salicylic acid is NOT a photosensitiser (SCCS confirmed: no photo-irritant, photosensitising, or photocarcinogenic properties). This is a major advantage. However, any exfoliating treatment weakens the outer skin barrier temporarily, so broad-spectrum SPF 30+ is still recommended as good skincare practice — but the heightened UV risk seen with AHAs does not apply.

Oil-soluble penetration requires caution: Salicylic acid's lipophilic nature allows deeper pore penetration, which is effective for acne but requires careful dosing. Start at 0.5–1% concentration, apply 2–3 times per week, and increase gradually as tolerance builds. Signs of over-use: persistent redness, irritation, peeling, or increased sensitivity.

GHS hazard codes apply to the raw material: The 10 GHS codes (including H361d for developmental toxicity) apply to concentrated salicylic acid. At cosmetic concentrations (0.5–3%) with buffered pH, the risk profile is substantially lower. Nevertheless, reproductive toxicity concerns warrant caution in pregnancy — see pregnancy section.

Prohibited for children under 3; concerns for 3–10: EU regulation: salicylic acid products cannot be marketed for children under 3 years. SCCS/1675/25 (April 2025) raised safety concerns for children 3–10 years at aggregate exposure to salicylic acid from multiple sources (skin care, cosmetics, medicinal products). Parental supervision and dose limiting are advised for this age group.

Not for spray or aerosol products: The SCCS advises against spray and aerosol formulations due to inhalation risk, particularly for young children and people with respiratory conditions.

Pregnancy & Nursing

Salicylic Acid carries GHS codes H361 and H361d ("suspected of damaging fertility or the unborn child" and "suspected of damaging the unborn child") for the pure substance — classified as Repr. 2 under CLP/GHS at the substance level, not a conclusion about cosmetic use. The SCCS referenced this classification and noted a NOAEL of 75 mg/kg bw/day, and that salicylic acid crosses the placenta. Unlike glycolic acid (where pregnancy data is simply limited), salicylic acid has a substance-level reproductive hazard classification and established placental penetration. Oral salicylates (aspirin) are known to cause developmental effects at therapeutic doses. At cosmetic concentrations (0.5–2%) with dermal absorption of up to ~60% under experimental conditions (real-world exposure considerably lower), systemic exposure is expected to be low. Topical salicylic acid at cosmetic concentrations is generally considered low risk, but many dermatologists recommend cautious use during pregnancy — particularly avoiding high concentrations or extensive body application. Limited use at the lowest concentration (0.5%) on small areas is generally regarded as acceptable. Consult your healthcare provider — alternatives such as lactic acid, azelaic acid, or physical exfoliants may be preferred during pregnancy depending on individual risk assessment. Nursing: limited data; caution is advised.

Safety data compiled from EU CosIng Database (#37595), CIR Expert Panel assessment, SCCS/1646/22 (Assessment of Salicylic Acid, June 2023), SCCS/1675/25 (Assessment of Salicylic Acid — safety concerns for children 3–10, April 2025), ECHA Annex VI GHS classification, SkinSenseDiary database analysis (7,115 products), and published clinical literature. This is for educational purposes only and does not constitute medical or dermatological advice. Always consult a healthcare provider before using salicylic acid products, especially during pregnancy or for children under 10. Last updated: April 2026.

How to Use Salicylic Acid

1

Cleanse Your Skin

Start with a gentle, pH-balanced cleanser. Avoid using a physical scrub or brush — combining physical and chemical exfoliation increases irritation risk. Pat skin dry before applying salicylic acid.

2

Apply Salicylic Acid (PM Recommended, AM OK)

Apply your salicylic acid product (toner, serum, or spot treatment) to clean, dry skin. Evening application is traditional, but since salicylic acid does NOT increase UV sensitivity (unlike glycolic acid), morning use is acceptable. Start with 2–3 times per week and increase frequency as tolerance builds. Avoid eye area and broken skin.

3

Wait, Then Moisturise

Allow salicylic acid to absorb for 5–10 minutes before layering other products. Follow with a hydrating, barrier-supporting moisturiser containing ceramides, hyaluronic acid, or niacinamide. This helps offset potential dryness and supports skin recovery, especially on sensitive areas like the eye and neck.

4

Sunscreen Every Morning (Good Practice)

Apply broad-spectrum SPF 30+ every morning. While salicylic acid does NOT increase UV sensitivity like AHAs, sunscreen is always essential as part of a healthy skincare routine. Any exfoliating treatment temporarily weakens the outer barrier and increases UV vulnerability during the exfoliation phase.

Which Product Format?

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Face Wash / Cleanser

Rinse-off format, typically 1–3% salicylic acid. Applied during cleansing for 30–60 seconds, then rinsed. Gentlest option; suitable for daily or twice-daily use. Good for beginners.

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Toner / Liquid

Leave-on format, typically 0.5–2% salicylic acid. Applied with a cotton pad after cleansing; absorbs quickly. Most popular format. Suitable for 2–5 times per week depending on concentration and skin type.

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Spot Treatment / Serum

Concentrated leave-on format, often 2–3% or higher for targeted application. Used on active breakouts or congested areas. Apply directly to problem areas only. Use 2–3 times per week. Professional peels can reach 20–30%.

Pairing Guide for Salicylic Acid

✓ Compatible Pairings

Niacinamide (Vitamin B3)

Excellent combination for acne-prone skin. Niacinamide strengthens the skin barrier, reduces sebum production, decreases inflammation, and improves post-inflammatory hyperpigmentation. Both work well together — this is one of the most recommended pairings for acne skin.

Hyaluronic Acid & Ceramides

Hydrating and barrier-repairing ingredients that offset salicylic acid's drying potential. Apply after salicylic acid has absorbed. This combination balances exfoliation with deep hydration and barrier support.

Sunscreen (Recommended)

Broad-spectrum SPF 30+ every morning is good skincare practice. Unlike glycolic acid, salicylic acid does not increase UV sensitivity, but the exfoliation process temporarily weakens the barrier. Sunscreen protects during this recovery phase.

⚠ Use with Care

Retinol / Retinoids (12 Hour Gap)

Conflict severity: HIGH (3/10). Both are potent actives that increase cell turnover and irritation. Using them in the same routine or evening risks over-exfoliation, redness, and barrier damage. Recommended: alternate evenings (Mon/Wed/Fri salicylic acid, Tue/Thu retinol) or separate by 12+ hours if using in same day. New users should NOT combine.

Vitamin C / Ascorbic Acid (8 Hour Gap)

Conflict severity: MODERATE (2/10). Both work best at low pH and can be individually irritating. Layering simultaneously may overwhelm the skin. Consider vitamin C in the morning and salicylic acid at night, or separate by 8+ hours. This pairing works for experienced users only.

Glycolic Acid / Other AHAs (24 Hour Gap)

Conflict severity: HIGH (3/10). Combining two exfoliating acids significantly increases irritation and barrier disruption risk. Never use salicylic acid and glycolic acid on the same evening. If combining in one routine, space by 24+ hours minimum (e.g., salicylic acid Monday, glycolic acid Wednesday). Over-exfoliation risk is severe.

Popular Products with Salicylic Acid

Found in 7,115 products in our database. Here are some well-known BHA options. Note: formulations change — always check the current INCI list on the product packaging or label.

Paula's Choice
2% BHA Liquid Exfoliant
Toner / Exfoliant
CeraVe
Salicylic Acid Cleanser
Face Wash
The Ordinary
Salicylic Acid 2% Masque
Mask / Treatment
COSRX
BHA Blackhead Power Liquid
Toner / Exfoliant
La Roche-Posay
Effaclar Acne-Prone Spot Treatment
Spot Treatment
Neutrogena
Oil-Free Acne Wash
Cleanser

Frequently Asked Questions

Is Salicylic Acid safe for sensitive skin?
Salicylic Acid has a SkinSenseDiary safety rating of 3/10 (low risk) and is classified as "Safe with Qualifications" by the CIR Expert Panel. It does NOT increase UV sensitivity (unlike AHAs) and is often better tolerated than glycolic acid for oily and acne-prone skin — though at higher concentrations it can be equally irritating. It is still an active ingredient and can cause irritation on very sensitive skin. Sensitive skin types should start with low concentrations (0.5–1%), apply 2–3 times per week, and always use a barrier-supporting moisturiser and sunscreen. The SCCS found low sensitisation risk at cosmetic concentrations (Buehler and LLNA tests negative) — most reactions are irritant-mediated, not allergic, though rare individual sensitivity may occur. Patch testing is advisable.
Can I use Salicylic Acid every day?
It depends on concentration. Low-concentration salicylic acid products (0.5–1.5% in cleanser or toner) can tolerate daily use after 2–4 weeks of tolerance building. Higher concentrations (2–3%) should be used every 2–3 days maximum. Signs of overuse: persistent redness, peeling, dryness, or increased sensitivity. Unlike glycolic acid, salicylic acid does NOT increase UV sensitivity, so timing is more flexible — you can use it morning or evening. Start conservatively: 2–3 times per week on all skin types, then adjust based on tolerance.
Is Salicylic Acid safe during pregnancy?
Salicylic Acid is classified as Repr. 2 under CLP/GHS (H361/H361d — suspected reproductive/developmental harm) at the substance level, not as a conclusion about cosmetic use. The SCCS noted a NOAEL of 75 mg/kg bw/day and that it crosses the placenta. Oral salicylates (e.g., aspirin) are known to cause developmental effects at therapeutic doses. At cosmetic concentrations (0.5–2%) with dermal absorption of up to ~60% under experimental conditions (real-world exposure considerably lower), systemic exposure is expected to be low. Topical salicylic acid at cosmetic concentrations is generally considered low risk, but many dermatologists recommend cautious use during pregnancy — particularly avoiding high concentrations or extensive application. Limited use at 0.5% on small areas is generally regarded as acceptable. Alternatives such as lactic acid, azelaic acid, or physical exfoliants may be preferred depending on individual risk assessment. Always consult your healthcare provider.
What concentration of Salicylic Acid should I use?
The SCCS recommends: ≤2% for leave-on face and body products; ≤3% for rinse-off (wash, shampoo); ≤0.5% for body lotion, eye care, lip care, deodorant, oral care, and antiperspirant; ≤0.5% as a preservative. Over-the-counter acne products typically range from 0.5–2% (face wash or toner) to 3% (rinse-off). Beginners should start at 0.5–1% concentration, applied 2–3 times per week, and gradually increase frequency as tolerance builds over 2–4 weeks. Professional peels and treatments can reach 20–30% but should only be applied by trained professionals. Concentration, pH, and formulation all affect efficacy and tolerability.
Can I use Salicylic Acid with Retinol?
This combination should be approached with extreme caution. Our database records a conflict severity of 3/10 (HIGH) with a 12-hour separation minimum. Both salicylic acid and retinol are potent actives that increase cell turnover and irritation. Using them in the same routine significantly increases the risk of over-exfoliation, redness, dryness, and barrier damage — potentially damaging long-term skin health. For safer use: alternate evenings (e.g., Monday/Wednesday/Friday salicylic acid, Tuesday/Thursday retinol), or if using in the same day, separate them by 12+ hours (morning salicylic acid, evening retinol — but NOT recommended for beginners). If your skin is exceptionally well-adapted to both at very low concentrations, some practitioners may allow sequential use with close monitoring. Prioritise barrier health over active ingredients. When in doubt, use them on separate nights.
Does Salicylic Acid increase sun sensitivity?
No. This is a key advantage of salicylic acid over glycolic acid. The SCCS confirmed that salicylic acid has no photo-irritant, photosensitising, or photocarcinogenic properties. It does NOT increase UV sensitivity or sunburn risk in the way that alpha hydroxy acids (AHAs) do. This means you can safely use salicylic acid in the morning without heightened UV vulnerability. However, sunscreen is still recommended as good general skincare practice — any exfoliating treatment temporarily weakens the outer barrier during the exfoliation phase, making skin more vulnerable to UV damage during that recovery period. Broad-spectrum SPF 30+ daily is ideal for all skin types, but salicylic acid specifically does not increase the urgency or necessity of sunscreen the way glycolic acid does.

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